Masataka Majima Selected Research

Stomach Ulcer (Gastric Ulcer)

1/2022	The role of thromboxane prostanoid receptor signaling in gastric ulcer healing.
3/2014	Vascular endothelial growth factor receptor 1 signaling facilitates gastric ulcer healing and angiogenesis through the upregulation of epidermal growth factor expression on VEGFR1+CXCR4 + cells recruited from bone marrow.
9/2013	NSAID, aspirin delays gastric ulcer healing with reduced accumulation of CXCR4(+)VEGFR1(+) cells to the ulcer granulation tissues.
11/2010	Role of microsomal prostaglandin E synthase-1 in the facilitation of angiogenesis and the healing of gastric ulcers.
1/2008	Roles of calcitonin gene-related peptide in maintenance of gastric mucosal integrity and in enhancement of ulcer healing and angiogenesis.

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Masataka Majima Research Topics

Disease

26	Neoplasms (Cancer) 01/2019 - 03/2002
10	Neoplasm Metastasis (Metastasis) 01/2020 - 06/2002
8	Inflammation (Inflammations) 01/2022 - 12/2002
8	Wounds and Injuries (Trauma) 01/2016 - 10/2006
7	Hypertension (High Blood Pressure) 01/2014 - 11/2002
6	Ischemia 01/2020 - 01/2010
6	Ulcer 03/2019 - 01/2008
5	Stomach Ulcer (Gastric Ulcer) 01/2022 - 01/2008
5	Fibrosis (Cirrhosis) 09/2019 - 11/2006
4	Endometriosis 10/2020 - 02/2011
4	Colitis 08/2020 - 09/2002
4	Lewis Lung Carcinoma 02/2014 - 10/2003
3	Necrosis 12/2020 - 02/2012
3	Ureteral Obstruction 01/2019 - 03/2015
3	Endotoxemia 10/2008 - 01/2004
2	Hepatic Veno-Occlusive Disease (Disease, Hepatic Veno-Occlusive) 07/2021 - 10/2019
2	Prostatic Neoplasms (Prostate Cancer) 01/2020 - 02/2013
2	Reperfusion Injury 01/2018 - 08/2013
2	Hepatitis 01/2018 - 04/2016
2	Lymphedema (Milroy Disease) 11/2017 - 09/2011
2	Lung Neoplasms (Lung Cancer) 12/2016 - 02/2014
2	Pain (Aches) 04/2011 - 02/2008
2	Sarcoma 180 08/2004 - 06/2002
2	Granuloma 09/2002 - 07/2002
1	Obesity 01/2022
1	Thrombocytosis (Thrombocythemia) 12/2020

Drug/Important Bio-Agent (IBA)

24	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 03/2002
14	ProstaglandinsIBA 01/2022 - 12/2002
9	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 02/2014 - 01/2003
8	Messenger RNA (mRNA)IBA 12/2020 - 11/2008
8	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2020 - 11/2002
7	Vascular Endothelial Growth Factor CIBA 11/2017 - 02/2010
6	ThromboxanesIBA 01/2022 - 01/2004
6	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 12/2020 - 02/2005
6	Prostaglandin-E SynthasesIBA 01/2020 - 12/2009
6	KininsIBA 01/2014 - 01/2002
6	SaltsIBA 01/2014 - 11/2002
6	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 02/2012 - 09/2002
5	CytokinesIBA 01/2022 - 04/2004
5	Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA 08/2020 - 03/2014
5	Prostaglandin E Receptors (Prostaglandin E Receptor)IBA 08/2020 - 10/2006
5	Calcitonin Gene-Related PeptideIBA 01/2020 - 01/2008
5	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 09/2019 - 09/2013
5	Neutralizing AntibodiesIBA 03/2014 - 10/2003
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2012 - 01/2004
5	BradykininIBA 03/2009 - 01/2002
4	Vascular Endothelial Growth Factor Receptor-3 (Flt 4)IBA 11/2017 - 02/2010
4	Celecoxib (Celebrex)FDA Link 03/2015 - 02/2010
4	Acetic Acid (Vinegar)FDA LinkGeneric 03/2014 - 01/2008
4	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 02/2014 - 10/2003
4	Dinoprostone (PGE2)FDA Link 02/2014 - 12/2009
4	Tissue Kallikreins (Tissue Kallikrein)IBA 01/2014 - 07/2002
4	Type 1 Angiotensin ReceptorIBA 02/2013 - 06/2002
4	2,5-dichloro-4-bromophenol (B 2)IBA 03/2009 - 01/2002
3	SodiumIBA 08/2020 - 02/2003
3	Proteins (Proteins, Gene)FDA Link 03/2019 - 11/2008
3	Leukotriene B4 Receptors (Leukotriene B4 Receptor)IBA 01/2019 - 08/2013
3	Angiotensin IIIBA 09/2017 - 02/2005
3	calcitonin gene-related peptide (8-37)IBA 04/2017 - 07/2008
3	Thromboxane Receptors (Thromboxane Receptor)IBA 07/2015 - 09/2004
3	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 03/2015 - 12/2002
3	Kallikreins (Kallikrein)IBA 01/2014 - 02/2003
3	Prostaglandins EIBA 09/2011 - 02/2010
3	Kininogens (Kininogen)IBA 01/2010 - 09/2002
3	N- (2- cyclohexyloxy- 4- nitrophenyl)methanesulfonamideIBA 12/2009 - 11/2002
3	FR 173657IBA 03/2009 - 03/2002
2	Alanine Transaminase (SGPT)IBA 12/2020 - 10/2019
2	Matrix Metalloproteinases (MMPs)IBA 12/2020 - 12/2016
2	Dextrans (Dextran)FDA Link 08/2020 - 04/2017
2	CXC ChemokinesIBA 01/2020 - 03/2014
2	Transforming Growth Factors (Transforming Growth Factor)IBA 09/2019 - 11/2010
2	Dextran SulfateIBA 03/2019 - 09/2002
2	Concanavalin AIBA 01/2018 - 04/2016
2	CollagenIBA 09/2017 - 05/2003
2	Vascular Endothelial Growth Factor DIBA 01/2016 - 05/2011
2	matrigelIBA 02/2014 - 05/2011
2	KATP ChannelsIBA 01/2014 - 03/2009
2	ebelactone BIBA 01/2014 - 01/2010
2	Antihypertensive Agents (Antihypertensives)IBA 01/2014 - 01/2010
2	PotassiumIBA 01/2014 - 01/2006
2	Leukotriene B4IBA 08/2013 - 07/2008
2	P-SelectinIBA 02/2013 - 04/2012
2	Interleukin-6 (Interleukin 6)IBA 02/2012 - 11/2008
2	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 05/2011 - 11/2010
2	Prostaglandin Receptors (Prostaglandin Receptor)IBA 05/2009 - 10/2006
2	candesartan cilexetil (Amias)FDA Link 02/2009 - 06/2002
2	AngiotensinsIBA 02/2009 - 09/2002
2	mofezolacIBA 10/2003 - 12/2002
2	Indomethacin (Indometacin)FDA LinkGeneric 12/2002 - 01/2002
1	ozagrelIBA 01/2022
1	Transforming Growth Factor beta (TGF-beta)IBA 01/2022
1	S 145IBA 01/2022
1	GlycolipidsIBA 01/2022
1	MonocrotalineIBA 07/2021
1	romiplostim FDA Link 12/2020
1	Thrombopoietin (c-mpl Ligand)IBA 12/2020

Therapy/Procedure

4	Ligation 01/2016 - 01/2002
3	Therapeutics 01/2018 - 02/2009
2	Intravenous Injections 01/2020 - 05/2003
2	Oral Administration 02/2014 - 03/2002